(pro)-SpCas9-SV40pA + U6-(gRNA)-(ins)

Minimal single-gRNA SpCas9 companion vector with a custom payload slot for co-delivery of an additional sequence element.

Characteristics

Expresses one gRNA from U6. Contains no fluorescent reporter — the insert slot is the primary functional addition beyond the gRNA, intended for a user-defined element such as an HDR template, second cargo gene, or regulatory sequence. Minimal footprint maximizes insert capacity.

Custom Inserts

SpCas9 gRNA target (20-23 bp) Long DNA

Literature Sources

    Available Products

    No products currently available with this design. Contact us for custom orders.

    Additional Information

    Applications: Single-target CRISPR editing requiring co-packaging of a custom sequence (e.g., HDR donor template, transgene, or additional expression cassette) in the same vector as the gRNA. Appropriate when no transduction reporter is needed or the insert itself provides a detectable marker.

    Fixed sequence length: 350 bp

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