Technology Guides

Technical primers on AAV serotypes, CRISPR systems, base editors, and gene delivery platforms—how they work and when to use them.

OpenCRISPR-1: The First AI-Designed Gene Editor

Gauri Paul | 22 Apr, 2026

The first gene editor designed entirely by AI and validated in human cells. OpenCRISPR-1 offers superior

Technology Guides

Gauri Paul | 16 Mar, 2026

Dual AAV systems split large transgenes across two vectors to bypass the 4.7 kb cargo limit. Early clinical

Technology Guides

Amir Saberi | 23 Dec, 2025

AAV vectors can package approximately 4.7 kb of genetic cargo. SpCas9 and its regulatory elements require

Technology Guides

Amir Saberi | 12 Mar, 2025

Discover strategies to reduce base editor size for AAV delivery in gene therapy. This insight explores

Technology Guides

| 09 Mar, 2025

From muscle to ocular applications, learn key serotypes, their tissue targets, and capsid engineering

Technology Guides