Human synapsin I (hSyn1/SYN1) promoter (~469 bp); pan-neuronal with strong activity in most CNS neurons. Among the most widely used promoters for AAV-mediated neuronal transgene expression in preclinical and translational neuroscience.
Length: 469 bp
Characteristics
Neuron-specific; drives broad expression across excitatory and inhibitory neurons. ~470 bp fragment sufficient for selectivity. Widely used in AAV vectors for CNS gene therapy and optogenetics.
