Rat nestin intron 2 enhancer fused to mouse Hsp68 minimal promoter
Rat nestin intron 2 enhancer fused to Hsp68 minimal promoter; restricts expression to CNS neural progenitor and stem cells, with activity declining as cells differentiate. Used to target transgenes to neural progenitors in the developing and adult brain.
Length: 1566 bp
Characteristics
~1.8 kb nestin intron 2 enhancer restricts expression to CNS neural progenitors when fused to Hsp68 minimal promoter. Inactive in differentiated neurons and non-neural tissues.
