Human cytomegalovirus immediate-early enhancer/promoter with human beta-globin intron 2 splicing signal
Human CMV enhancer/promoter fused to the beta-globin chimeric intron; the intronic element boosts expression approximately 5–10-fold above CMV promoter alone, making this one of the strongest mammalian expression cassettes available.
Length: 1242 bp
Characteristics
CMV IE enhancer/promoter fused to β-globin intron 2 splice donor/acceptor; enhances mRNA stability and nuclear export, boosting expression ~5–10× versus CMV alone.
