Synthetic muscle creatine kinase 8 enhanced (CK8e) promoter
Synthetic enhanced muscle creatine kinase (CK8e) promoter (~450 bp); combines MCK regulatory elements with poorly conserved regions removed, driving strong expression in both skeletal and cardiac muscle. Specifically designed for compact AAV gene therapy vectors.
Characteristics
Compact ~1 kb synthetic promoter combining MCK regulatory elements after removal of poorly conserved regions. Drives strong skeletal and cardiac muscle-specific expression; optimized for AAV gene therapy.