Mouse alpha-calcium/calmodulin-dependent protein kinase II (CaMKIIα) promoter (8.5 kb)

Mouse CaMKIIα promoter, 8.5 kb; provides the most selective targeting of forebrain excitatory (glutamatergic) neurons in cortex, hippocampus, and striatum. Preferred in transgenic mice requiring strict restriction to excitatory neurons.

Length: 8023 bp

Characteristics

Forebrain excitatory neuron-specific (cortex, hippocampus, striatum). 8.5 kb; best specificity for glutamatergic neurons. Preferred in transgenic mice requiring strict forebrain restriction.

Sequence

aagcttcgatcttttttccgtaaactcaataccaggctgatgtcccaccggatctgatggcttagggtggcagggaatctcagttcccctcagacactctccctttgctggttctcagggaggaggcaaggtcaagtcttcatctgtaggcacgtggagggagggcacagaagccctcagctgaatagggtgggacttggggaagggcagcaaccaggctgggttgcctgggtcacaatcctgcctctttcctgatgagtttcctttttgccctcaggttacctatagcagcattctgcctcaatctcacccctaagatgagctctggtgactttaggactccagtgtacacatgtgtctggggccatggcagggtttcttgctgaccttgtcaccttccagacaacttgagtccatgaccctctttccagctctctgtggtgctcttggatatcagctggagtatggccagctggctgctgctctgttgaacaactcaatgagagaacggacagggtaggctctgagaaatctttacgttcctggagcctcatgacttgggagcctagtggaattcttctcttttggtccccaacatctggggggagggggaactggctgagcctgagccactgtatagtgagggtgggggaaacagctgtgaaaggagcctttgatttggtcttgaacacagttcttccccacagggccttgatttccctacttgcaaaggagtagggaaatatgagccttggctctgcctacctcacgttgctggtgctgtagaaaactggccaggctgatggttgtggaggagcctgtgaacttgattaaagtgccattatccagaggcaagagatgctggtctgtgtgtgtgtgagtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtcttggagacctgtgtgagctcgatgctagcagaggggacagaaggtaggtgggaaggaatgaaggaatgaaggaaggaaagaaggaaggttgaaaggaagaaaggaaggaaggaaggaaggaaggaaggaaggaaggaaggaaggaaggaaggaaggaaggtcctgccacaggcttaccatgtagctgcaggcaaacccctgaccctctctgggcctaagtgtttctctacacacaatggatgattcaagagtccttacttttggtggttacaggcacccctgtgcacatttgcatctggggtgggggggacacaggcttggtagtgttgaggaggggggtggttgtagagcctgctagctgcacactgcgttctgcatatctcccttcaggtcccagtcggcgcagtgtgtgtaggcgaaggccctgctgtgaattttgaaaatagttatttttgtcactggcaaaggaggccctgttaggactcgtcagcttgtggatgagcgggatgggtggagtggggtgggtgcggtgccgccgtggggggttaccgctgcttgcagggctgcatcgcccaggcagtgactgaatcctgcatgagggcctggcctaggctgtggggaggagatgaccactgcgtcctagatctttccttagccctgtgcttcctttcttccttttttccttaagatttatttctaatgatgcgtaggttgtgtatttgtgtgtgggtatgtgcacttgaataaaggacccacagaggctatagacatcagatcctcctagagctggggttacagagggcgtgagttgtccaacatgggcaccggaaaataaacttatgtgctctacacgaccgagctgtctctccaacaccagccctcttcttttgacttttctcatctccctcacttgtatgttttcccttcctcgataatgctgatacccagatggtaggcacggcccaggataggcaggggtctctgcgctccagtggctgtagtggttttcctgcctgctctgaagaagacactggctaaggtggtgtcttagcctactgtatcctagaggtgggttattcatagtctgcccactgcccaacacactctaggcctgctggggcctattctaactctgcttgctggcttgccaccctggcacacagtgtaggcttccctgtagagccaggctttagagaactgtatgagtacttctctgagaactgctggaggggccctgcctgccaggacttttcaacttccagccctgtcatctatatcacttctgaggaccccgtgtgggggtcacgagaacaagaccatatgtagtgctttctgttctcccttgggtcccaggctctgaatcaatctggtcccaagatataagggatgattggtgctgaggctggtgtctgtttctgaagttttgaagacaagggttggctcaagcctccctgtgttcagtcctccactcaatgcagaactcagtgaactcagaattctcagcccagatgccagcatagcccagcatagcccagcatagcccaggagctactggagcatcagtttgaaaccaggtccgcaggaactagtgggcaacagtgtgtgaggccagtggtctttggggtattgtattgaattgagaggtcctgcttagcagtcagcatgcccacaacctgttctctacggtggtccggattcccctcagcaagcacacctgaatctttactacatcccagttcctggttggctcctgacttcgggttactatggctgtgatgaaacactacgactaaaagcaatgtggggaagaaagttaattttttcactcgaccttccatagacagggttcatcactaaaagcagagggcagaggaaaagatagctcagcggttaagagtgctgtctactcaacaaagaggtcttgagttcaattcccagcaaccacatggtggctcacaactgtctatcctgggatctgatgcccttttctggcatacaggtatacatacagatagaggactcatatacataaaataaataaataaatctttaaaagcaacaagggcagaaattcaagcagggcagggacccagaggccaaagctgacgcagaggccatggaggggtgttgcttactggcttgctcctcatggcttgctcagcctgttttcttatagaacccacaaccaccaggccagagatgggaccacccacaaagggcagagcctttccctatcaatcactaatgggaaaacatcctgcagtcggatcttatgaagacattttctcagctgagcttccctcctatcagataactctagcttgtgtcaaggtgacttaaaactagccagcacagcaccttatgctcacatcacctgggtccctttggagaggacatagttaaagggagcccagaggcagtccctaggccacaggtcttcattgcccctctctgggacggattagacaggctgcagacctgttagctggaagagttagattcaggcaagagcttgaatctttacctgatcctggctatggagtcctggcctctaatgatcagctccctaacaacccaatggagccatatacctgcctgggccacggctgtgtctcctcttctttcagacactcctggcttgcctaggacacaggctagcatcctgtcaatgccaggaaggggcacagcagggaaagagcaatgctgttggcctgactgccatcaactggtgtacctgttagagggcaacctctattctctgcaccttggttcctagctctaagggatatgtggcccctaaaggtcttcatagcttgatatgggaggcaggggggctaagaacagcgcaagagtggtgagcttgcacagacccggatttgatctctgggtgagtgaggaggaaatgagatgggggtgggggaagccctatttctagctgtcttagcataggaactgaacctccttctgcagggcctgtgtcactgcccctttcccccagggagggcccctgcacggggcacctcagggcacagccctttttccctccctcctctcttagacctggaattactcaacatcctgccctgactcagttgctctcccctcagaccctcacagtcttccttctcttctggcccacttttggctgagcctgcccccaactttttctgcccttagtgggacaggccccatggggaccattcagatggcacttttttccccccctggggtggttttctgtggtggtgccctattcaggcaactgcaagaccctgtggcatttagcatatgcatgagagcacatgaagaagctagctatccctgtgtgctgaggattgtaatcctctctcatccttcccttgtctcctggaacccagtccagcctcctgtccctcccgttgacacgagccaatgctggctcagcaaactccagggctcccacccctggccatcagcccttggcacacaggcttgtgcttgagtactgcacacgtgttgcagctggggtacacgtgctggactgttatgcctactgtggccccgggggtgtgtgggaagtctggcagaaccaatccctccatcccccgatgcaatcatcagcttattctctcacggccactcgggcatgcttgactccttgatgcccgccgccactaggcacagctgccagctttgtgggcacagaggatgtggcgaattagtggtcatgcctcctcagtggaatggcaattgcactcagcatgcaggtgtctaccaaaggcagtccctacatccccgatgtactctcgagacccatctaaggactagatctagtctctagaaggtcccatgcagatgtaagacagccctccacagggagattcttccagctagttctctattatcagatgggtctaagatcctaggacctgcctatcccttagccctgcattcagcgagagaaggggtaaagatgtgaggatgccagggaggaaggaaaagggcacaaggaagaaagaaagggaaggaagctggaagcatggaaggacaaagatggtgaccacagtagaattaggatcccatggttcctgtcagtggcttcctgtgccttcctgtgcctccctgagcccctggggcatcttctaaatgctttgctggcctctgagccaagcactgcataccatcccgtggggagtgacaggccagcactggtcaacgaggatgatggctacttttgttcacagggtaacatctccatggttacagcctttgcacattcctcttagtactttaccaatctcaaagcagttgccaagcccttgggccctaataagtgagggtcccagtgccctcttttttaaattccttgccatttgttttgcagaatttactgcaaataaagccaaccccaggcaatgtctaaaccatgagttaaccccccagcaaggtctcagagaactgtgccccagagagctgccaaggttcagggaggagtatgaggagacaggatttctagttccttaataattccttctgtctcagccactgtgttcatcttgtttcagccacaaaactacctttattggtaaggaacattatttacccagtttcacacttgaagaggtccagagacgttaacacatcgattcaaaagcacagcctgtaagtcacatagccactgttagctgatcgacactatttcccctgggcaatggctgggtgattccagggatccccttgggaacaggctagagcactggctctcaacctgtgcgggtcgtgacctccttgaggggtaggggtgagggcagtgtcaaacaacccttttacaggagtcgtttaagaccgttgggaaaaaaaccagatatttgcattatttttcgtaacagaagcaagattatagttatggagtagtgacaaaaattatgttacagttggaggtcagcacagcatgaggaactgtatttaagggttgcggcattaggaaggttgagaatcactggcctagcggatctgaatcaggaacacggacgtacagctctgcgccactcctgccttcctctggtgcctctagccttgcccatggtgttctgggcctgcctgctacccaccagctgtgcggccctgtgagcacaggcctttctgctccgctctgaattgccacgttggcggcagaagcgggaagcgtattgtgcgcagaaacaaaacggagtggttttttttttcctttttctgaaggtggtaatggtgcaattagtggcgaagccatcaccccctcctccccggctcgcctccctccttcctctccacctcccttctctttctttcctgagaaaaaaagtggctgagttgaaaagatctcccgtcaatctttctgtaacggactcaggaagagggatagagggccccctaatgtttccagggtcctcgagcctcagttgggtcaggcacttgttggtgctggagaatattcaaaggtaccactatgttccccacaagggagttgagcaatggattctgaggagcaagtttgaaacagagaatttgcgttcccaggtcttgtgatctgccccttgttcactgggggacaaatgctggcatgagaccctgagacctctgctcagccacctttctctctctctctctctttctctctctctctctctctctctctctctctctctctctctctctctgtccttaatggaggtgtgtgtgtgttcaagaccaagctgcagtgttggagtgcttgtgggctcattttaaaacttccatgttttgccttctagaaactgaaacataagaaccccattatggccttaggtcacttcatctccatggggttcttcttctgattttctagaaaatgagatgggggtgcagagagcttcctcagtgacctgcccagggtcacatcagaaatgtcagagctagaacttgaactcagattactaatcttaaattccatgccttgggggcatgcaagtacgatatacagaaggagtgaactcattagggcagatgaccaatgagtttaggaaagaagagtccagggcagggtacatctacaccacccgcccagccctgggtgagtccagccacgttcacctcattatagttgcctctctccagtcctaccttgacgggaagcacaagcagaaactgggacaggagccccaggagaccaaatcttcatggtccctctgggaggatgggtggggagagctgtggcagaggcctcaggaggggccctgctgctcagtggtgacagataggggtgagaaagcagacagagtcattccgtcagcattctgggtctgtttggtacttcttctcacgctaaggtggcggtgtgatatgcacaatggctaaaaagcagggagagctggaaagaaacaaggacagagacagaggccaagtcaaccagaccaattcccagaggaagcaaagaaaccattacagagactacaagggggaagggaaggagagatgaattagcttcccctgtaaaccttagaacccagctgttgccagggcaacggggcaatacctgtctcttcagaggagatgaagttgccagggtaactacatcctgtctttctcaaggaccatcccagaatgtggcacccactagccgttaccatagcaactgcctctttgccccacttaatcccatcccgtctgttaaaagggccctatagttggaggtgggggaggtaggaagagcgatgatcacttgtggactaagtttgttcgcatccccttctccaaccccctcagtacatcaccctgggggaacagggtccacttgctcctgggcccacacagtcctgcagtattgtgtatataaggccagggcaaagaggagcaggttttaaagtgaaaggcaggcaggtgttggggaggcagttaccggggcaacgggaacagggcgtttcggaggtggttgccatggggacctggatgctgacgaaggctcgcgaggctgtgagcagccacagtgccctgctcagaagccccaagctcgtcagtcaagccggttctccgtttgcactcaggagcacgggcaggcgagtggcccctagttctgggggcagcgggggatccactagttctagagcggccgc

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