St1Cas9 Nuclease

Length: 3400 bp(1133 aa)

PAM: NNAGAAW

Origin: Streptococcus thermophilus (CRISPR1)

Characteristics

Compact Cas9 variant suitable for AAV packaging. More restrictive PAM than SaCas9. Used primarily when SaCas9 PAM availability is insufficient. Moderate editing efficiency.

Literature References

  1. Müller et al. (2016). Streptococcus thermophilus CRISPR-Cas9 systems enable specific editing of the human genome. Mol Ther - Müller 2016 St1Cas9

Related collections

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