RNA targeting with CRISPR-Cas13

Abudayyeh et al. (2017). Nature DOI: 10.1038/nature24049 Citations: 2084

Parts used

Cas13a RNA-Targeting Nuclease

Key findings

  • Characterized Cas13 for programmable RNA targeting without DNA cleavage. Demonstrated RNA knockdown, editing, and tracking. Established RNA-level CRISPR applications.