MyoAAV-4A Serotype
Fourth myoAAV variant from M-CREATE selection, completing the muscle-targeted AAV toolkit with distinct properties.
Characteristics
Additional M-CREATE isolate with unique characteristics. Balanced skeletal and cardiac muscle transduction. Cross-species validation. Alternative pharmacology to other myoAAV variants.
Applications
Multi-muscle tissue gene therapy. Systemic muscular dystrophy treatments. Translational applications.
Literature References
- Tabebordbar et al. (2021). Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species. Cell - Tabebordbar 2021 MyoAAV
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