AAVmyo2 Serotype
Second-generation AAVmyo variant with improved diaphragm and limb muscle transduction profile.
Characteristics
Enhanced diaphragm transduction. Improved limb muscle coverage. Reduced off-target biodistribution. Capsid shuffling optimization.
Applications
DMD with respiratory involvement. Diaphragm-targeted gene therapy. Limb-girdle muscular dystrophies.
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