AAV8BP2 Serotype
Bioprocessing-optimized AAV8 variant engineered for enhanced manufacturability with improved thermal stability and production yields.
Characteristics
Improved thermal stability. Higher production yields in manufacturing. Maintained wild-type AAV8 tropism profile. Enhanced scalability for clinical production. Favorable bioprocessing characteristics.
Applications
Clinical-scale liver gene therapy. Hemophilia gene therapy with improved manufacturing. Large-scale AAV production applications.
Literature References
- Markusic et al. (2010). High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines. Mol Ther - Markusic 2010 AAV8BP2
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