AAV6.2 Serotype
Naturally occurring AAV6 variant with distinct capsid sequence and improved transduction characteristics in muscle and liver.
Characteristics
Natural AAV6 variant with distinct capsid sequence. Enhanced transduction efficiency versus AAV6. Improved tissue penetration. Foundation for AAV6.2FF development.
Applications: Muscle gene therapy. Hepatic applications. Alternative to wild-type AAV6.
References
- Rutledge et al. (1998). Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2. J Virol - Rutledge 1998 AAV6
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