AAV-PHP.V Serotype
Vascular endothelium-targeted PHP variant for blood vessel gene delivery applications.
Characteristics
Second-generation CREATE for vascular targeting. Enhanced endothelial cell transduction. BBB endothelial specificity. Novel application beyond neuronal gene therapy.
Applications
Vascular biology research. BBB manipulation studies. Endothelial gene therapy approaches.
Literature References
- Huang et al. (2019). Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids. Neuron - Huang 2019 PHP Variants
Related collections
-
AAV Vectors
Adeno-associated viral vectors for in vivo and ex vivo gene delivery. From...
-
CRISPR Tools
Comprehensive CRISPR components for custom genome editing workflows. Guide RNAs, nuclease variants,...
-
Base Editing
Precision single-nucleotide conversion without double-strand breaks. Adenine base editors (A→G), cytosine base...
-
Prime Editing
Search-and-replace genome editing without double-strand breaks or donor templates. Prime editors enable...
