Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Gao et al. (2002). Proc Natl Acad Sci USA DOI: 10.1073/pnas.182412299 Citations: 2065

Key findings

Isolated AAVrh.74 and AAVrh.10 along with other rhesus-derived serotypes from NaHP tissue. Demonstrated lower human seroprevalence than AAV2, offering immune evasion advantage for gene therapy applications.